Clarke County is a county in the Commonwealth of Virginia. As of the 2020 census, the population was 14,783. Its county seat is Berryville. Clarke County is included in the Washington-Arlington-Alexandria, DC-VA-MD-WV Metropolitan Statistical Area.

Cities: Berryville, Boyce
Population: 15,266 (2022)
Congressional district: 6th
Largest town: Berryville
Named for: George Rogers Clark